Chemical decellularization: a promising approach for preparation of extracellular matrix
نویسندگان
چکیده
منابع مشابه
Preparation of a three-dimensional extracellular matrix by decellularization of rabbit livers.
INTRODUCTION the availability of transplantable livers is not sufficient to fulfill the current demand for grafts, with the search for therapeutic alternatives having generated different lines of research, one of which is the use of decellularized three-dimensional biological matrices and subsequent cell seeding to obtain a functional organ. OBJECTIVE to produce a decellularization protocol f...
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Extracellular matrix (ECM) hydrogels are used as scaffolds to facilitate the repair and reconstruction of tissues. This study aimed to optimize the decellularization process of porcine skeletal muscle ECM and to formulate a matrix hydrogel scaffold. Five multi-step methods (methods A-E) were used to generate acellular ECM from porcine skeletal muscle [rinsing in SDS, trypsin, ethylenediaminetet...
متن کاملCrosslinking strategies for preparation of extracellular matrix-derived cardiovascular scaffolds.
Heart valve and blood vessel replacement using artificial prostheses is an effective strategy for the treatment of cardiovascular disease at terminal stage. Natural extracellular matrix (ECM)-derived materials (decellularized allogeneic or xenogenic tissues) have received extensive attention as the cardiovascular scaffold. However, the bioprosthetic grafts usually far less durable and undergo c...
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ژورنال
عنوان ژورنال: Biomedical Papers
سال: 2015
ISSN: 1213-8118,1804-7521
DOI: 10.5507/bp.2013.076